Centec preparation containers are designed for the production of liquid pharmaceutical products . The aim is repeatable product formulation with very precise process control – from filling to dispensing of the finished product.


 Application
 
 
 liquid medicines
 
 
 Infusion solutions
 
 
 Syrups
 
 
 Vaccines



 Process flow
 1) Filling with WFI
 
 
 The container is first filled with water for injection ( WFI ).

 2) Dosing & dissolving of raw materials
 
 
 Pre-weighed raw materials (e.g. concentrates, powders) are added.
 
 
 A circulating pump dissolves the raw materials in the water.

 3) Precise level control
 
 
 Differential pressure gauges and load cells are used for accurate level control .

 4) Repeatable formulation through strict regulation
 
 
 Temperature and pressure in the container are controlled within narrow limits to achieve optimal and repeatable product formulation .

 5) Sterile product dispensing
 
 
 At the outlet of the container, the finished product flows through a sterile filter .



 Hygiene design & equipment
 The design is geared towards very good cleaning and sterilization properties .
 Many components are available as options, e.g.:
 
 
 agitators
 
 
 Homogenizers
 
 
 valves
 
 
 Measuring instruments
 
 
 Sampling equipment



 Your advantages at a glance
 
 
 Vertical or horizontal ; single-walled or multi-walled design
 
 
 Many optional components for highly accurate process control
 
 
 Frame-mounted for easy installation and commissioning
 
 
 Hygienic design and full CIP/SIP capability
 
 
 In accordance with applicable guidelines (e.g. cGMP, FDA, GAMP, ISPE )
 
 
 Fully qualified (DQ, IQ, OQ) if desired



 Technical data
 Capacity: 10 – 20,000 l (others on request)
 Operating pressure: -1 to +6 bar
 Operating temperature: max. 150 °C
 Material: 1.4404/1.4435/AISI 316L; etc.
 Surface quality: Ra < 0.4 and others possible; electropolishing possible
 Ferrite content: < 1% possible


 Options (depending on the version / project-specific)
 
 
 Measurement of critical parameters such as pressure, temperature, concentration, pH, O₂
 
 
 insulation
 
 
 agitator
 
 
 Homogenizer



 contact
 For design, documentation scope (DQ/IQ/OQ) and integration into your line, please use the contact form below.


 Modular design & extensions
 Formulation container
 Dosing system – volumetric or gravimetric
 CIP system pharmaceuticals
 CIP – Cleaning in Place
 Valve Block – Valve blocks
 Distillation plant (WFI) – Multi-column distillation
 Loop return – monitoring/control unit
 Loop distribution station – media distribution