PW generator – Ultrapure water system for pharmaceutical water quality
The PW Generator is a modular system for the production of pharmaceutical purified water (PW). The concept starts with the treatment of raw water or drinking water and leads through defined pretreatment and desalination stages to the required purity level according to pharmaceutical standards. The hygienic piping design, the possibility of drainability, CIP of the system – including individual desalination modules – and comprehensive automation support GMP-compliant operation.
Application
The PW Generator is used for the production of pharmaceutical purified water (PW) in accordance with the requirements of:
- European Pharmacopoeia (Ph. Eur.)
- United States Pharmacopeia (USP)
System Design (from raw water to PW)
1) Pretreatment (depending on water quality / system design)
- Softening
- Activated carbon filtration
- Particle filtration
- optional UV disinfection
2) Desalination / conductivity reduction and degassing
To reduce conductivity and non-condensable gases, the following units are used depending on the system design:
- single-stage or double-stage reverse osmosis
- degassing system
- electrodeionization (EDI)
- ultrafiltration (UF)
Hygienic Design & Operational Safety
The piping design is developed to prevent microbial growth inside the system.
In addition, the following features are provided:
- drainability of the system
- CIP – including individual desalination modules
- surface finish < 0.8 µm according to requirements; lower surface roughness possible depending on the version
- numerous sampling points for safely controlled PW production
Automation & GMP Integrity
The automation system monitors critical parameters and supports system integrity within the GMP framework, including:
- conductivity
- TOC
- temperature
- pressure
Special Features / Characteristics
- Hygienic, CIP/SIP-capable design according to GMP requirements
- PW capacity can be designed within a defined from/to acceptance range
- AISI 316L electropolished; welds according to DIN / ASME BPE
- FDA, EMA, cGMP, and GAMP-compliant design
- Automation via Siemens or Rockwell PLC with remote access
- Integrated sensor technology for conductivity, TOC, and online microbiological measurement
- Modular skid design for easy installation and future expansion
Benefit
Consistently high-purity water quality according to pharmaceutical standards with minimal operating effort and full GMP compliance.
Areas of Use
For use in industrial pharmaceutical and biotechnology plants to supply purified water for:
- cleaning
- CIP/SIP
- formulation
- further processing applications
Technical Data
Capacity: 500 – 50,000 l/h
Material: AISI 316L (material no. 1.4404)
Product water conductivity: < 1.3 µS/cm at 25 °C (according to USP / Ph. Eur.), possible down to < 0.1 µS/cm
Total Organic Carbon (TOC): < 500 ppb TOC
Operating temperature: 20 – 25 °C
Options (depending on version / project-specific)
- CIP/SIP-capable
- Automation (Siemens / Rockwell PLC)
- remote access
- online measurement (TOC, conductivity, microorganisms)
Contact
For system design, automation, and the appropriate documentation scope for your PW infrastructure, please use the contact form below.