Distillation plant (WFI) – Multi-stage distillation plant
The plant operates on a multi-column principle: Pre-treated water is evaporated in stages, and the vapor condenses into WFI. Special separation and demiser technologies ensure that droplets or impurities do not enter the vapor.
The construction in AISI 316L stainless steel with electropolished surfaces enables GMP-compliant operation and easy cleaning/validation. Full automation ensures continuous monitoring of quality (e.g., conductivity, pressure, temperature) and process reliability.Special features / characteristics:
- Hygienic design in AISI 316L with highly polished surfaces
- Proven multi-column distillation process for short shutdown phase to achieve the required quality with stable plant operation
- Validable documentation (DQ, IQ, OQ)
- Fully automated with control, data logging and alarm functions
- Droplet separation for high WFI quality
- Acceptance samples across a wide performance range from / to
- Energy optimized through the use of multiple evaporation/condensation stages and the use of preheaters
👉 Advantage:
Reliable and verifiable production of WFI quality according to pharmacopoeia standards – ensures the highest purity and process safety in pharmaceutical production environments.
Application:
The distillation plant produces WFI quality for pharmaceutical applications (e.g., injection solutions, hemofiltration, sterile cleaning) in accordance with the United States Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.).
Technical data:
parameter specification capacity Customized, typical range 300 – 11,000 l/h material AISI 316L (material 1.4404) Proceedings Multi-column distillation (e.g., falling-film / multi-effect) Temperature range Condensate temperature approx. 85–95 °C in the last process step Conductivity of product water PW quality < 1.3 µS/cm at 25 °C (WFI standard, depending on the entry) TOC < 500 ppb (according to pharmaceutical monograph) Options DQ/IQ/OQ, simultaneous intake of pure steam